The antibody J43 is an anti-mouse PD-1 (CD279) antibody. It is produced by Bio X Cell and is specifically formulated for in vivo use. The antibody reacts with mouse PD-1, which is a cell surface receptor that belongs to the CD28 family of the immunoglobulin superfamily. PD-1 is expressed on various immune cells, including T and B lymphocytes, and plays a role in regulating immune responses. The J43 antibody has been shown to block the binding of PD-1 ligands to PD-1 and has been used in studies investigating the role of PD-1 in cancer and autoimmune diseases.
For more information, you can refer to the following links:
1. Bio X Cell: InVivoMAb anti-mouse PD-1 (CD279) - J43
2. Thermo Fisher Scientific: CD279 (PD-1) Antibody (clone J43)